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How does hydroxyurea work in sickle cell disease? Hydroxyurea, a myelosuppressive agent, is the only effective drug proven to reduce the frequency of painful episodes. It raises the level of HbF and the haemoglobin level. It usually decreases the rate of painful episodes by 50 %. It was first tested in sickle cell disease in 1984.
Can nurse practitioners prescribe medications? Nurse practitioners can now prescribe controlled drugs and substances. The Nurses (Registered) and Nurse Practitioners Regulation was amended July 26, 2016 to include the prescribing of controlled drugs and substances as within the scope of practice for nurse practitioners (NPs).
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