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What does rifampin do to bacteria? Rifampicin works by killing the bacteria that are causing the infection. It does this by targeting and inactivating a bacterial enzyme called RNA-polymerase. The bacteria use RNA-polymerase to make essential proteins and to copy their own genetic information (DNA).
How long after taking rifampin can I eat? To do so may increase the chance of side effects. This medicine should be taken on an empty stomach, 1 hour before or 2 hours after a meal, with a full of glass of water. It is important to take this medicine on a regular schedule.